Brazilian federal police said they were after 15 people on Tuesday in relation to the corruption investigation which focuses on state-run oil producer Petroleo Brasileiro SA, police said.
Tuesday's operation, codenamed "Xepa", revealed a bribe-payment scheme headed by engineering conglomerate Odebrecht SA, police said in a statement without giving the names of the targets.
It is the 26th raid since the corruption probe started two years ago and has put top executives and political leaders in prison.
The new raid has also raised chances of the impeachment of President Dilma Rousseff.
Opposition parties in Brazil first opened impeachment proceedings against President Dilma Rousseff in September 2015. She was accused of violating Brazil's fiscal laws and manipulating government finances to help her get re-elected in 2014.
In a televised address to the nation, Rousseff expressed her "outrage" at the accusations and said there was no evidence of any wrongdoing by her.