Three million people in the Chilean capital were without drinking water on Saturday after heavy rain caused landslides that fouled the rivers supplying the city, officials said.
The national emergency response agency declared a red alert in Santiago, a city of more than seven million people.
"Unfortunately the weather system over the metropolitan region brought rain that caused increased sediment in the Maipo River, which means a water cut for the population affecting about three million people," Santiago Mayor Claudio Orrego told a news conference.
Production was down to 35 percent of normal levels, said Eugenio Rodriguez, corporate manager of the Aguas Andinas water company.
Heavy rains in the Andean foothills since Friday triggered landslides into the Maipo and Mapocho rivers.
Municipal authorities activated an emergency plan that includes tapping into 45 backup water sources and mobilising more than 60 water trucks.
Images shared on social media showed bare shelves at supermarkets, where thousands flocked to stock up on bottled water.
In the O'Higgins region 90 kilometres south of Santiago, the swollen Tinguiririca River left one person missing and about 100 homes damaged.
Four municipalities in the region were also on red alert.
Rain was expected to continue throughout the weekend.