Thirteen people died and 34 others were wounded when two trucks collided in southern Cuba, local media reported on Tuesday.
The deadly accident happened in Santiago de Cuba province, Agencia Cubana de Noticias announced.
Among the wounded, five are in critical condition according to reports.
Police are investigating the cause of the collision.
As a result of Cuba's long-running economic crisis, the Communist government in the country prefers to use cheap trucks for people movers rather than to import costly buses.
Cuba has a population of around 11 million and there have been more than 10,000 recorded traffic accidents in the country within this year, and 615 people have lost their lives.