Grammy-winning singer Natalie Cole, the daughter of Nat King Cole, has died at the age of 65, according to US media reports.
The TMZ celebrity news website said Cole died from congestive heart failure following complications from a kidney transplant and Hepatitis C, diagnosed in 2008.
Cole, who had struggled with drug problems in the past, scored a big hit in 1991 with "Unforgettable" - a virtual duet with her late father, who died before his daughter began her solo career.
"Unforgettable" and the album it came from earned Cole three of her nine Grammy Awards.
"#NatalieCole, sister beloved & of substance and sound. May her soul rest in peace. #Inseperable," the Rev. Jessie Jackson posted on Twitter.
"#NatalieCole.. Condolences to family. What an incredible woman, a loving. joyful & peaceful soul. Rest in peace," Democratic strategist Donna Brazile said in another tweet.