At least 1,300 refugees were rescued from the Mediterranean Sea over the past 48 hours with 16 bodies recovered, the Italian coastguard said on Monday.
People fleeing war and poverty risk their lives with the possibility of drowning in the Mediterranean, for a better future in Europe.
On Sunday, the Italian coast guard ship Diciotti discovered 11 bodies on a boat which had run into difficulty, while a commercial vessel intervening at another boat found three dead.
The Aquarius, a relief vessel chartered by SOS Méditerranée and Doctors Without Borders (MSF), meanwhile, said efforts to resuscitate two women found on a dinghy had failed.
"Two women died of hypothermia in spite of the colossal efforts of the team. We are heartbroken, again," MSF said on Twitter.
The reasons for the other deaths were not specified, but burns or fuel inhalation can prove fatal to already weakened refugees setting off from crisis-hit Libya, where abuse and torture is rife.
A turn in the weather over winter usually slows departures, but the pace has remained steady this year while the number of NGO vessels patrolling off Libya has dropped sharply.
A total of 285 refugees were rescued on Saturday, 791 on Sunday and 231 on Monday.
All were packed into small wooden boats or inflatable dinghies which often begin to sink after just a few hours at sea.
Among those pulled to safety were a number of Syrian families travelling with young children.
Most of the over 173,000 refugees who have arrived this year in Italy have come from West Africa and the Horn of Africa.
At least 4,700 people have died or are missing feared drowned this year while trying to cross the Mediterranean, the United Nations estimates.