DAESH has claimed responsibility of a large-scale car bombing on Saturday in the central city of Homs near a hospital killing 16 people and wounding dozens, a monitoring group said.
In a statement, the terrorist group DAESH said that the attack was executed by a suicide bomber named Abu Ahmad al Homsi, who blew his vest up after parking and detonating the car.
The Governor of the city Talal Barazi said that the attack took place near the Al-Ahli hospital in the Al-Zahraa neighbourhood where most residents are from the Alawite sect, in which the leader of the Syrian regime Bashar al Assad is a member.
Around 54 people were wounded in the attack, some of them remain in critical condition. The Britain-based Syrian Observatory for Human Rights (SOHR) said that the death toll is 16 but it is expected to rise as there were many who were heavily injured in the attack.
The attack comes three days after hundreds of rebels and civilians were evacuated from the city after a deal with the regime.
According to the deal managed by the United Nations, the besieged neighbourhood Waer, the last rebel-held neighbourhood in Homs surrendered to the regime forces in exchange for humanitarian aid.
"The explosion was terrifying. Body parts were on the ground... It was one of the biggest explosions to hit Homs," a 28-year-old woman who witnessed the explosion told AFP.
"The blast left a huge crater, and people were running in every direction in fear of more explosions," she added.
The war in Syria started in 2011 after peaceful demonstrations demanding freedom and better living conditions were suppressed by the Syrian regime.
Russia and Iran have been supporting Assad and forces loyal to him, while Turkey, Saudi Arabia, the US and other western countries support the rebel groups.
Moscow launched an air campaign on September 30 in support of Assad, targeting Assad opponents mainly opposition groups based in the west of the country.
The Syrian conflict paved the way for the emergence of the terrorist group DAESH which declared the formation of a self-proclaimed caliphate in Syria and Iraq in 2014 with the Syrian city of Raqqa as its capital.
A US-led coalition launched an aerial campaign to fight the group in September 2014.
According to UN estimates, the war in Syria has so far claimed the lives of over 250,000 people, while the Syrian Observatory for Human Rights says that the true death toll exceeds 350,000.