At least 27 people, including 16 children died as scores were reported wounded after an explosion resulted in a fire at a clinic in the northwestern Syrian province of Hasakah, with the death toll expected to rise.
A statement released by the Local Coordination Committees of Syria reported that the blast took place in the Maysaloun neighbourhood of Qamishli city.
A local activist who wished to remain anonymous told al-Jazeera that the blast was caused by a gas explosion in the clinic and killed at least 40 people.
"The fire took place east of the city at the Maysaloun clinic. We had just begun a vaccination campaign for the children," a local activist who requested to remain they said.
"The death toll could rise to 50, including nurses, women and children. We found 18 burnt bodies, it was horrific," he added.
The blast came after Syrian regime air strikes rattled the city overnight killing at least 65 people, including 43 fighters from ISIS and 22 civilians, according to the London based Syrian Observatory for Human Rights.
The Hasakah province came under attack by ISIS last week, aiming to take control of the province from a unified front of Marxist Kurdish People’s Protection Units (YPG) fighters (the Syrian branch of the outlawed PKK group recognised as a terrorist organisation by the EU, US and Turkey), regime loyalist militias and regime soldiers.
No information is yet to be given as to whether or not the blast was the result of an attack and no immediate responsibility has been taken.