The Red Cross also said more than 600 attacks on health workers had been reported in connection with the Covid-19 crisis.
The United Nations paid tribute to humanitarian workers now battling the Covid-19 pandemic after a year in which they found themselves under greater attack than ever before.
The UN marked its World Humanitarian Day on Wednesday by remembering the 125 aid workers who were killed in 2019, and the hundreds of others who were wounded or kidnapped.
"The UN condemns these attacks, and it calls for accountability for perpetrators and justice for survivors. Relief workers cannot be a target," said OCHA, the UN Office for the Coordination of Humanitarian Affairs.
The day was to see a wreath-laying at the United Nations in Geneva, in a ceremony attended by UN rights chief Michelle Bachelet.
According to the Aid Worker Security Database compiled by the Humanitarian Outcomes research group, major attacks against humanitarians last year surpassed all previous years since records began in 1997.
In 277 separate incidents around the world, a total of 483 relief workers were attacked, of which 125 were killed, 234 wounded and 124 kidnapped.
The figure represents an 18 percent increase in the number of victims compared to 2018.
Most of the attacks occurred in Syria, followed by South Sudan, the Democratic Republic of the Congo, Afghanistan and the Central African Republic.
In 2019, 483 aid workers were subject to attacks, the highest number ever recorded.— UN Humanitarian (@UNOCHA) August 19, 2020
.THIS.MUST.STOP.NOW. Humanitarians are #NotATarget.https://t.co/2TIyipT3yE #WorldHumanitarianDay pic.twitter.com/ejIGBwRqsB
Humanitarians, health workers & first responders are the unsung heroes of the #COVID19 response – often risking their own lives to save others.— António Guterres (@antonioguterres) August 19, 2020
On #WorldHumanitarianDay, join me in thanking them for their work, solidarity & humanity in this time of unprecedented need. pic.twitter.com/F68Bfa9lAr
The UN said aid workers and healthcare responders were now going to extraordinary lengths to help people whose lives have been upended by crises, and now by the global Covid-19 pandemic.
"This year, humanitarian workers are stretched like never before," said UN Secretary-General Antonio Guterres.
"They are responding to the global crisis of Covid-19, and with it the massive increase in humanitarian needs from the fallout of the pandemic.
"They are the unsung heroes of the pandemic response and they all too often risk their own lives to save the lives of others."
OCHA added, "In recent weeks alone, despicable attacks have killed aid workers in Niger and Cameroon, and since the onset of the pandemic, scores of health workers have come under attack across the world."
On August 9, six French aid workers were killed at a wildlife haven in Niger.
World Humanitarian Day is held on the anniversary of the August 19, 2003 attack on the UN compound in Baghdad which killed 22 people.
Mark Lowcock, the UN's emergency relief coordinator, said, "The best way to pay tribute to humanitarian workers is by funding their work and ensuring their safety."