At least 21 people were injured, one of them seriously, after an Iranian retaliatory missile struck Tel Aviv, as explosions echoed across the city during a new wave of launches from Iran, the daily Yedioth Ahronoth reported.

An Anadolu correspondent reported a massive explosion in the city following the strike, while large blasts were also heard in Tel Aviv and air raid sirens sounded in Jerusalem.

The Israeli army said it detected a new barrage of missiles launched from Iran and urged residents to move to protected areas, according to a statement.

The United Arab Emirates said it shot down 132 Iranian ballistic missiles and intercepted 195 drones.

The Defence Ministry said 137 missiles were detected, with five falling into the sea, while 209 drones were tracked, including 14 that landed in UAE territory or waters, causing limited collateral damage.

US Secretary of State Marco Rubio will no longer travel to Israel on a trip announced for Monday after a joint US-Israeli attack on Iran, the State Department said.

"Due to current circumstances, Secretary Rubio will no longer travel to Israel on March 2," Dylan Johnson, the assistant secretary of state for global public affairs, wrote on X.

The Iranian ambassador to the United Nations slammed the US and Israel for committing a "war crime," saying their strikes had targeted civilian infrastructure and killed more than 100 children at a school.

"The number of innocent civilians continues to rise. This is not only an act of aggression, it is a war crime and a crime against humanity," Amir Saeid Iravani told an emergency meeting of the UN Security Council.

Israel's emergency service Magen David Adom has reported that an Iranian missile strike left one woman dead, injured 21 people in the area of Tel Aviv, including one person in critical condition.

MDA said in a statement it evacuated 20 casualties to the hospital including one man in serious condition and gave treatment on site to "a woman in her 40s who is unconscious and in critical condition with serious injuries".

AFP journalists and Israeli television channels reported first responders and firemen deployed in several parts of Tel Aviv, and physical damage to the city.

President Donald Trump has said that the US bombing of Iran will continue as long as needed.

"The country has been, in only one day, very much destroyed and, even, obliterated. The heavy and pinpoint bombing, however, will continue, uninterrupted throughout the week or, as long as necessary to achieve our objective," Trump posted on his Truth Social platform.

Russia's UN envoy strongly condemned the latest US and Israeli military attacks on Iran, calling them "another unprovoked act of armed aggression."

"Washington and West Jerusalem's actions are nothing other than yet another unprovoked act of armed aggression against a sovereign and independent UN member state in violation of the charter of the organisation and of the fundamental principles of international law," Vassily Nebenzia said during an emergency session at the UN Security Council.

The UN special rapporteur on the right to housing accused the US and Israel of "destroying world peace and order" as tensions in the Middle East escalate after both countries launched strikes against Iran.

Balakrishnan Rajagopal, in a post on X, said, "I strongly deplore the attack on Iran by US and Israel and the cowardly complicity of States who approve this or stay silent."

He stressed that "so many innocents will die and people’s homes destroyed because of this."

Italian Defence Minister Guido Crosetto was stranded in Dubai with his family due to the temporary suspension of flights following US and Israeli attacks on Iran, according to the ANSA news agency.

Crosetto had travelled on a civilian flight from Rome on Sunday to join his family, with plans to return together to Italy.

Air traffic in the region was halted amid heightened security concerns after the attacks, preventing the minister's return.