The driver of the bus lost control while negotiating a turn and rammed into a tree in the Nyamakate area, near the border with Zambia.
A bus accident in Zimbabwe has killed 43 people after the driver lost control and rammed into a tree, police said Thursday.
"We have been told that 43 people have been killed," police spokeswoman Charity Charamba said.
"The bus was travelling to Zambia when the driver lost control at a curve yesterday evening," she said.
Charamba said the crash occurred in the Nyamakate area, near the border with Zambia.
Cross-border coaches usually ferry traders from Zimbabwe who travel to Zambia to stock up on wares to sell back home.
Last year at least 30 people were killed when two buses collided along the highway connecting the capital Harare and Bulawayo.
Road accidents are common in Zimbabwe, where highways are riddled with potholes due to years of neglect. Several other accidents claiming dozens of lives have occurred in the past months.