The $400 billion agreement includes economic and cultural interaction between the two sides and also paves the way for Iran's participation in the Belt and Road initiative.
China has said it will begin implementing a strategic agreement with Iran, strengthening economic and political cooperation between the two countries as Beijing blasted Washington's sanctions on Tehran.
Chinese foreign minister Wang Yi and Iranian counterpart Hossein Amirabdollahian announced the start of the partnership's implementation at a meeting in east China's Wuxi on Friday, Beijing 's foreign ministry said in a statement.
The foreign ministers agreed to step up cooperation in energy, infrastructure, production capacity, science and technology, and medical and health care, the sides said in statement according to China's state-owned CGTN.
Bilateral cooperation will also be expanded to agriculture, fisheries, cybersecurity and the third party market, as well as people-to-people and cultural exchanges in education, film and personnel training, said the statement.
Speaking to reporters in Beijing after his meeting with Chinese counterpart Wang Yi, Amirabdollahian said the two countries have made "adequate arrangements" to set the agreement in motion, hailing it as "one of the important achievements" of the trip.
China also reaffirmed its opposition to unilateral sanctions by the United States against Iran.
Wang, who is also State Councillor, said the US bore primary responsibility for the ongoing difficulties with Iran, having unilaterally withdrawn from a 2015 nuclear deal between the major powers and Iran.
The $400 billion agreement between Tehran and Beijing was signed on March 27 last year by then Iranian Foreign Minister Javad Zarif and Wang during latter's visit to Tehran.
The agreement includes economic and cultural interaction between the two sides and also paves the way for Iran's participation in the Belt and Road initiative, a massive infrastructure project stretching from East Asia to Europe.
The project aims to significantly expand China's economic and political influence, and has raised concerns in the United States and elsewhere.
The Chinese foreign ministry said the agreement would deepen Sino-Iranian cooperation in areas including energy, infrastructure, agriculture, culture, as well as cyber security and cooperation with other countries.
The accord had last year stirred up a hornet's nest in Iran as many feared that it would open up Iran's strategic ports to Chinese investments and military bases. However, officials have dismissed these reports.
The agreement was envisaged in 2016 when Chinese leader Xi Jinping visited Iran soon after a nuclear deal was signed between Iran and the world powers.
However, after the US withdrawal from the deal in May 2018, followed by the reinstatement of sanctions, the Iran-China agreement was also put on the backburner.