The casualty figure, provided by locals and rescuers, is preliminary and is expected to rise.
The blast struck an entrance to the city, killing civilians including children, the UK-based Syrian Observatory for Human Rights says.
In northern Syria, residents are returning to villages that were once controlled by the YPG. Turkey's military and the FSA pushed the terror group out of the Afrin region in recently but rebuilding lives is likely to be a slower process.
A former YPG recruit says he was kidnapped from his home by the group when he turned 18 and then was forced to serve at one of its camps in Syria's Afrin region.
After Turkish troops and the Free Syrian Army drove the PKK-linked YPG out of the Syrian town of Afrin, locals are returning now that the situation has stabilised.
The group of Arab, Kurdish, Alawite and Yazidi residents of Afrin gathered across the border in Gaziantep to discuss Afrin's future, after Turkey's military and its FSA allies liberated the town on Sunday.
Turkish military footage shows civilians trying to leave the town despite YPG/PKK attempts to block their way.
Erdogan says civilians are being led out of Afrin through a special corridor as the Turkish military and Free Syrian Army encircle the centre of the town.
There have been reports of a deal between the YPG and the Syrian regime on Afrin to stop Turkey’s operation. Russia opposes the plan unless the YPG hands over all its arms provided by the US. Iran supports the plan that its proxies control the city.
The pro-regime militants consisted of a convoy of 20 vehicles that departed from the Nubl al Zahraa region and tried to advance into Afrin region.
A barrage of regime air strikes, rocket fire, and artillery slammed into several towns across the opposition-held Syrian enclave, killing and wounding hundreds, according to a war monitor.
Turkish President Recep Tayyip Erdogan points to a potential future mission in Syria's Afrin region, which is controlled by the YPG.
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