No one claimed responsibility for the bombing but President Ashraf Ghani blamed Taliban insurgents despite the spokesperson for the militant group denying links to the attack.
Neither Daesh not the Taliban have yet claimed responsibility for the attack that took place in Mihterlam, the provincial capital of Laghman province.
Car bomb targets government building in Ghani Khel district of eastern Nangarhar province, killing at least 15 people and wounding nearly 40 others, officials say.
At least five civilians were killed after an explosives-laden vehicle blew up in the town of Azaz. No one has claimed responsibility for the attack yet.
Meanwhile, the US has said its deal with the Taliban is in the "next phase" as it urged the militants to reduce rising bloodshed.
An official said a grenade and a car bombing were used to attack the Southern Border Provinces Administration Center in the capital city of Yala province.
Officials say the blast, also wounding more than 120 people, targeted a tax collection centre in capital and most of those killed were university and other students. Two Turkish brothers are among the dead.
Turkey's defence ministry says PKK/YPG attack in the village of Tal Halef, near the city of Ras al Ayn, also wounded more than 20 people.
More than 20 people wounded as two car bombs and an explosives-rigged motorcycle blow up in a market and near a school in Qamishli city, a Britain-based war monitor says.
The casualty figure, provided by locals and rescuers, is preliminary and is expected to rise.
The car bomb exploded in the rebel-held Syrian city of Idlib, killing two people and injuring at least 11 others.
Another two dozen people were wounded as a bomb exploded outside a hotel near the international airport in Somalian capital Mogadishu, officials say.
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