Barcelona will have to improve significantly to match Bayern Munich in the quarter-finals, who are arguably favourites to win the tournament.
Zinedine Zidane had never lost a knockout tie in the Champions League as Real manager, having won his previous 12 encounters while winning the trophy three times, and City manager Pep Guardiola noted the significance of the victory.
A goal up after winning February's first leg, French side Lyon will face Manchester City at the final tournament in Lisbon after drawing 2-2 on aggregate and going through on away goals.
With his record, Cristiano Ronaldo could lay claim to the top scorer title in Serie A.
Seven months after leaving Pep Guardiola's side, Mikel Arteta outwitted his mentor to ensure his first season as Arsenal manager will end with an FA Cup final.
The plan is to go to Lisbon for a unique "final eight" straight knockout tournament from the quarter-finals onwards, starting on August 12 and finishing with the final at Benfica's Estadio da Luz on August 23.
Alvaro Morata scored twice to help Atletico Madrid to a 3-0 win over relegation-haunted Mallorca and stretch their unbeaten La Liga run to 12 games, as the victory consolidated their third place on 62 points to stay well on course.
With no fans in the stands on a wet night in Bremen, it was a subdued and strange celebration for Bayern’s players, who put on commemorative T-shirts and paid tribute to their absent supporters with cheers.
Under the plan the competition, which was suspended in March due to the coronavirus pandemic, will resume with the second-leg of remaining last 16 games played at the scheduled venues.
While the virus is still affecting everyday life in Britain, the return of the Premier League, albeit behind closed doors, will offer a welcome distraction for football-starved fans.
Man City are accused of overstating sponsorship revenue to hide that they had not complied with UEFA's financial fair play (FFP) rules between 2012 and 2016.
Football players in Germany contemplate staging collective protests following the police killing of unarmed black man George Floyd in the United States.
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