The International Red Cross estimates that about 4.2 million people were affected by the back-to-back Category 4 hurricanes in November in Honduras, Nicaragua and Guatemala.
Iota is about 475 km east of Isla De Providencia Colombia and expected to become a major hurricane as it approaches Central America.
Turning streets to rivers, Sally was the second hurricane to hit the US Gulf Coast in less than three weeks and the latest to blow during one of the busiest hurricane seasons ever.
At least six people have been killed after the hurricane flooded streets, submerging or destroying buildings, and leaving more than 700,000 people without power in Louisiana and neighbouring Texas.
The National Hurricane Centre said Isaias was strengthening slightly with sustained winds just under a Category 1 hurricane.
Bahamian meteorologists said the islands of Grand Bahama and Abaco, which were the worst-hit by Hurricane Dorian, were in the path of the approaching weather system.
NBC, citing a representative for Prime Minister Hubert Minnis, said the official count is now 43 and the number is expected to rise significantly.
Hurricane Michael strengthens to a Category 3 storm as Florida declared a state of emergency for 35 counties from the Panhandle to Tampa Bay.
Officials say the death toll from Hurricane Florence, now a tropical depression, has jumped to at least 32.
Hurricane Florence remains a major hurricane despite being downgraded to a Category 3 storm.
Residents of the tiny British islands in the Atlantic are urged to remain indoors, as the Category 4 storm approaches with wind speeds over 200 kilometres per hour.
Residents in Haiti and Jamaica have been ordered to evacuate as Cuba suspended flights in preparation for the worst storm to hit the Caribbean in almost a decade.
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