The man was shot in the head during a protest near the village of Beit Dajan, near Nablus, and was taken to a hospital where he later died.
Israeli forces fired rubber bullets as well as tear gas canisters to disperse dozens of Palestinians marching in protest against Israeli illegal settlements in Deir Jarir in Ramallah city.
Fifty percent of Israelis support annexation, half of them only with US support, and
nearly 31 percent oppose annexation of Palestinian lands, says a new poll published by Israel Democracy Institute.
In the Israeli-occupied West Bank, people are living through double isolation amid a one-month state of emergency.
Mohammed Hamayel, 15, "died as a result of being shot in the face with live ammunition by the (Israeli) occupation" during clashes in Nablus, Palestinian Health Ministry says.
Mohammad Shtayyeh took the post of prime minister after the former prime minister resigned six weeks ago. The post comes with a tough mandate at a time when Palestinians have been completely sidelined.
Israel's domestic intelligence agency Shin Bet, said the teens "are suspected of grave terrorist offences including murder."
Israeli forces have killed three Palestinians in raids in the occupied West Bank, saying one of them was sought over an alleged drive-by shooting near the West Bank settlement of Ofra in October.
Ahmad Abu Obeid was shot in the head during an Israeli army incursion into the village of Burqin in the northern West Bank.
The confrontation near a military post occurred when an Israeli settler in a car attempted to drive through a crowd of Palestinian protesters.
US officials have adopted a more forceful tone with Netanyahu's government in recent weeks, accusing it of recklessly accelerating construction despite international concern.
Palestinian security source says Israeli Army arrested 21 Palestinians including two Hamas leader
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