Three-time prime minister Nawaz Sharif has twice been removed from office - in 1993 by a presidential order and in 1999 by a military coup that saw him jailed and later exiled before returning when General Pervez Musharraf stepped down.
Pakistan's supreme court on Friday banned former prime minister Nawaz Sharif from participating in elections for life, as his embattled ruling party prepares for nationwide polls due later this year.
The ruling was the latest in a series of blows to Sharif who was ousted from the premiership over graft allegations last July.
Supreme Court Justice Umar Ata Bandial described the ban on Sharif as "permanent" in a judgement read to the court, clarifying the length of an earlier ruling that disqualified the former premier from office.
TRT World spoke to Islamabad-based journalist Kamran Yousaf for more details.
The decision was immediately panned by Sharif's ruling Pakistan Muslim League-Nawaz party (PML-N).
"Today once again, the three-time elected prime minister of Pakistan has been disqualified for life," state minister and Sharif ally Maryum Aurangzeb told reporters outside the court.
A member of Sharif's ruling party, Information Minister Maryam Aurangzeb, angrily dismissed the ruling as a "joke."
The court also banned disqualified opposition politician Jahangir Tareen from running for office again.
Last month, Nawaz's brother Shahbaz Sharif formally took charge of the PML-N after an earlier court ruling banned the former premier from heading the party.
The Sharifs and their supporters have repeatedly denied allegations of corruption, suggesting the former prime minister is the victim of a conspiracy driven by Pakistan's powerful military establishment.
Sharif was the 15th prime minister in Pakistan's 70-year history – roughly half of it under military rule – to be removed before completing a full term.
The court ruling comes months ahead of expected general elections, pitting the PML-N against its main rival, the Pakistan Tehreek-e-Insaf party led by former cricket star Imran Khan.
Despite the numerous court rulings against the PML-N, the party has won a string of recent by-elections proving it will likely remain a force in the next polls.