Idlib's civil defence, a rescue service in opposition-controlled territory known as the White Helmets, says air strikes over the past 24 hours have hit several villages in the northwestern province.
More than 40 children were among those killed in the strikes which leveled the municipality building in Syria's Al Mayadin, according to the Britain-based Syrian Observatory for Human Rights monitoring group.
The Trump administration fired 59 cruise missiles at a Syrian air field on Friday in response to a chemical attack on the town of Khan Shaykhun last Tuesday.
A senior Russian general has accused the US-led coalition of targeting infrastructure in Syria - including Tabqa Dam, Syria's biggest clean water supplier.
The Syrian Observatory for Human Rights along with local sources say dozens were killed in two coalition air strikes this week.
After spending six months in a Syrian prison, Hasan Othman won the election to become "mayor" of a Syrian refugee camp in Turkey. His supporters need Othman as much as Othman needs them.
The idea of revolution continues to smoulder in Syrians as they try to rebuild their lives in refugee camps in southern Turkey
The offensive comes as the Turkey-backed Free Syrian Army (FSA) forces continue to make their way toward the strategic city of Al-Bab, in northern Aleppo.
The bomb that is causing immeasurable human tragedy in Syria has also been used in the past.
CENTCOM yet to release number of dead or injured over the past week.
The US-led coalition strikes came a day after the coalition opened a formal investigation to determine whether its air strikes last week near Manbij claimed more than 100 civilians including children.
A number of nations, including the Unites States, Turkey, UK, France, Iran, Russia, Saudi Arabia, other Gulf allies of the US and the Syrian regime, are involved in the Syrian conflict.
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