The bombardment on southern rebel-held areas came barely hours after the US warned the Syrian regime not to jeopardise talks on the fate of the Daraa region.
Syrian foreign minister Walid al-Moualem says that apart from Daesh and rebels, the US needs to withdraw from a strategic base in the southwest of the country.
The US warning comes following Syrian regime's attack on a de-escalation zone in northeastern Syria held by US-backed Syrian Democratic Forces.
The Syrian regime says it has retaken the last neighbourhoods in southern Damascus held by Daesh and declared the capital and its surroundings "completely safe" from militants for the first time in nearly seven years.
The same day Trump announced he was pulling out of the nuclear deal, Israel launched several attacks on Iranian-militias and regime-held areas in Syria, signalling a potential escalation between the two regional foes.
Two-day meeting in Astana aimed at ending Syrian conflict will address developments in de-escalation zones, release of captives and forming a constitutional committee.
Israel's raids against Iranian positions in Syria led to calls for calm from Russia, France, Germany, Britain and the European Union while Israeli Prime Minister Benjamin Netanyahu said Iran had "crossed a red line."
The regime continues to pound opposition and rebel-held areas in Syria, and Idlib is expected to be the site of the next big assault. However, unlike the previous battles, Turkish troops' presence in Idlib may complicate matters.
Syrian regime media accused Israel of launching missiles against its forces near Damascus.
An advanced Russian multi-role fighter plane crashed in Syria on Thursday after take-off, killing both members of its crew, the Russian military was cited as saying by Russian news agencies.
A regime assault killed 17 civilians, including seven children on Friday in the Palestinian camp of Yarmouk in southern Damascus, the Syrian Observatory for Human Rights said.
The exercise is part of an ongoing investigation into the suspected chemical attack by the Syrian regime that killed dozens in the enclave on April 7. Meanwhile, the world donors have pledged $4.4 billion for people affected by Syrian war.
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