There are expectations the meeting will have a different tone from last year when wary world leaders weren't prepared for US president's brand of diplomacy or for his determination to push an "America first" agenda.
UN draft resolution expresses grave concern over three reported chlorine attacks in Eastern Ghouta in recent weeks and asserts that those responsible for using chemical weapons must be held accountable.
Real peace in the Middle East seems to be at this moment in doubt as the US remains at odds with most of the world over its decision to recognise Jerusalem as Israel's capital.
Some UN Security Council members, including France and Russia accuse Washington of meddling in Tehran's domestic affairs.
As the United Nations faced serious challenges this year arbitrating in old and new disputes, here's a quick take on what lies ahead of it in the coming year.
Trump must decide in mid-January if he wants to continue to waive energy sanctions on Iran.
The painting smashed the world record for any work of art sold at auction. The buyer's name is not yet known.
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