The 22-year-old was the first woman to win the US Open singles final from a set down since 1994.
World number one Novak Djokovic is sensationally disqualified in fourth round after striking a female line judge inadvertently with a ball following a point during a match against Spain's Pablo Carreno Busta.
Murray wore a coronavirus-conscious mask on his way to the unusual, no-spectators setting and avoided handshakes when he left. In between, the three-time Grand Slam champion offered his usual mix of hustling and muttering.
The 33-year-old Serbian has won five of the past seven men's singles Slam crowns but came to the US hardcourts only after assurances from European officials that players returning from the US would not face a long quarantine before upcoming events.
The former Australian, Wimbledon and US singles titleholder, was part of the golden era of Australian men's tennis in the 1950s, winning four major singles titles and four in doubles.
Russian Maria Sharapova burst onto the scene as a supremely gifted teenager and won her Grand Slams before serving a 15-month ban for failing a drugs test at the 2016 Australian Open.
Serena Williams was the bookies' favourite to win a record-equalling 24th Major at Melbourne Park but she came unstuck against a determined Wang, who won 6-4, 6/7 (2/7), 7-5 – after taking only one game the last time they met.
All of the early scheduled matches on the outside courts at Melbourne Park got under way on time while several matches previously suspended due to the poor air quality or the rainfall were rescheduled to resume play later on Thursday.
Djokovic's win gave Serbia an unassailable 2-0 lead ahead of the doubles to set up a meeting with either the Nick Kyrgios-led Australia or Rafael Nadal's Davis Cup champions Spain in the final.
David Goffin claims an upset 6-4 7-6 (3) victory over world number one Rafael Nadal in Sydney to keep Belgium alive in their quarter-final clash at the inaugural ATP Cup team event.
Casper Ruud, a product of Nadal's tennis academy in Mallorca, has beaten top-20 players John Isner and Fabio Fognini to make his mark at the international teams tournament in Australia.
Naomi Osaka has withdrawn from the WTA Finals because of a right shoulder injury ahead of her scheduled round-robin match against top-ranked Ash Barty.
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