Iraqi officials said that twelve civilians have been killed and five wounded in an explosion on a bus at the main checkpoint for the northern entrance to Karbala.
The accident occurred at a major shrine where Shia pilgrims were marking the holy day of Ashura. Officials say another 100 people are injured.
The expulsion of Daesh from Iraqi cities added an extra dimension to this year's pilgrimage.
"They beat us, slaughtered us and burnt our houses," says an elderly man, forced to flee the brutality of Myanmar's military. Our correspondent writes from a camp in Bangladesh, where Rohingya refugees are living in conditions unfit for animals.
Most of the people killed in the attack were Iranian nationals who were returning from the city of Karbala after an annual pilgrimage.
The attack targeted Shia worshipers who had gathered at the mosque to mark the end of a 40-day mourning period for the death of Imam Hussein, the grandson of the Prophet Muhammad.
Five out of six attackers were killed before they could detonate their explosives, according to a statement by Iraq's interior ministry.
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