Cities and towns along the critical highway linking Damascus with Aleppo have become sites of brutal destruction at the hands of the Syrian regime.
The Britain-based Syrian Observatory for Human Rights, an opposition war monitor, said rebels withdrew from Idlib province's Maarat al Numan town late on Tuesday.
The air strikes and artillery shelling targeted the village of Basqala and nearby places, according to the Syrian Civil Defence rescue group, also known as White Helmets.
No immediate information on casualties from the strike on Rahma hospital in Tal Mannas.
The opposition and rebel withdrawal came after the Russia-backed Syrian regime forces advanced into Khan Shaykhun city in Idlib. The US urged the regime to revert to a ceasefire in Idlib after Monday's air strike on a Turkish convoy.
A war monitor says "fierce clashes" between loyalist forces, militants and allied rebels were taking place one kilometre west of Khan Shaykhun in Idlib province.
A pilot who ejected from the plane was captured, says Syrian Observatory for Human Rights after militants shoot down a regime warplane in Idlib province.
The push towards Khan Shaykhun threatens to encircle the last remaining pocket of opposition and rebel territory in neighbouring Hama province, including the towns of Morek, Kafr Zeita and Latamneh.
A family that left everything behind in the Syrian town of Khan Shaykhun due to the air strikes by the regime forces share their ordeal.
Regime forces strike eastern Ghouta's Douma district in a midnight attack allegedly using a chemical agent, rescuers and medics say, sparking condemnation and retaliation vows.
The White House urged the United Nations to renew the probe into a chemical attack on the opposition-held town of Khan Shaykhun that killed dozens of people last April.
UN findings backs claims by the US, France and Britain that a Syrian regime plane dropped a bomb with sarin on the town and falsifies Russia's claims that a bomb on the ground was the cause of the gas attack.
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