The blast occurred in Helmand province where both the Taliban and Daesh are said to be active.
The explosion took place in Ali Sher district of Khost province. Interior Ministry spokesperson Nasrat Rahimi said three children, two women and five men were killed.
CIA-funded paramilitaries are wreaking havoc in Afghanistan.
Meanwhile, around 100 Afghan soldiers fled their posts and tried to cross into neighbouring Turkmenistan during a weeklong battle with the Taliban in the western Badghis province.
The victims had all gathered to attend Friday prayers at a mosque inside an Afghan army base in Ismail Khel district of Khost province.
A suspected suicide bomber killed at least 14 people in Khost province. In Badghis province, fighting between militants and security forces left at least 36 people dead.
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