Real Madrid’s struggles in the Spanish league continued as city rivals Atletico moved level with leaders Real Sociedad after extending their winning run to six matches.
The two members of Atletico Madrid's group were set to travel to Portugal for the Champions League quarterfinals against RB Leipzig in Lisbon.
Barca once again failed to build on an early advantage and were forced to grind out the victory in the second half as Valladolid took the game to them.
Substitute Ivan Rakitic scores in the 71st minute to help Barcelona win 1-0 against Athletic Bilbao bringing the Catalans back to the top of the La Liga. Second placed Real Madrid face Real Mallorca on Wednesday.
The second of Europe's five major leagues, La Liga, kicked off in Spain as two local rivals, Sevilla and Real Betis met in a hotly contested derby behind closed doors.
Junior sports minister Irene Lozano has said fans will not be able to attend matches when the season resumes on June 10.
Debate has raged ever since the French league decided to bring a premature end to the season in late April with 10 rounds of matches unplayed.
No matches have been played in the Premier League since March, but the government has given the green light for elite sport to resume from June 1, including the top-flight football.
In normal circumstances, the German game, dominated in recent seasons by Bayern Munich, lacks marketing pull of England's Premier League or Spain’s La Liga, which boasts the world’s two biggest clubs in terms of revenue, Barcelona and Real Madrid.
Spanish newspaper El Pais reported that Real Madrid forward Luka Jovic had injured himself training at home in the Spanish capital and said he would be out for around seven weeks.
Unlike other European countries, Spain is set on completing its football season with players and staff having to undergo a month's worth of tests before being able to return to full group trainings.
Spain's Health Minister Salvador Illa says it would be "imprudent" to promise resumption of football season before summer in country where Covid-19 has claimed more than 23,000 lives.
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