The former Sampdoria boss suffered four defeats in his first seven games, including a 2-0 loss to rivals Inter Milan. Former Inter coach Luciano Spalletti, 60, is first choice to replace Giampaolo, Italian media report.
Francesco Totti will play his final game for AS Roma, but it is not clear if the 40-year-old will hang up his boots altogether or play for another club.
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