The bus was travelling from Cairo when it turned over and was hit by the truck on a road in the southern province of Assiut, 320 kilometres south of Cairo.
A large goods transport vehicle hit three other vehicles at high speed, including two buses, due to a braking system failure in the city of Goma, the local mayor said.
The accident took place around dawn Tuesday as the bus, with 48 passengers, was heading from the Amazon rainforest city of Puerto Maldonado to the highland city of Cusco.
Police say another 15 people were hurt when a bus on educational tour plunged down a mountainous slope and rolled about 1,640 feet in western Nepal.
Fully loaded truck crashes into van on a cross-country highway near the town of Khairpur, about 1,040 km south of the capital, Islamabad.
32 schoolchildren, believed to be aged between 12 and 13, were killed in the crash in the northern region of Arusha.
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